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Lymphatic Filariasis (LF)

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February 15, 2025

Why in News?

Union Health Minister launched National Mass Drug Administration (MDA) campaign for the elimination of Lymphatic Filariasis (LF) across 13 identified LF endemic states.

  • Lymphatic filariasis (LF) – It is a Neglected Tropical Disease (NTD).
  • Caused by – Parasites classified as nematodes (roundworms) of the family Filariodidea.
  • There are 3 types of these thread-like filarial worms
    • Wuchereria bancrofti, which is responsible for 90% of the cases
    • Brugia malayi, which causes most of the remainder of the cases
    • Brugia timori, which also causes the disease.
  • Causes – It damages the lymphatic system and the kidneys and alter the body's immune system.
  • It is commonly known as Elephantiasis or Hathi Paon.
  • SymptomsAsymptomatic, acute and chronic conditions which leads to,
    • Lymphoedema (tissue swelling) or elephantiasis (skin/tissue thickening) of limbs and hydrocele (scrotal swelling).

  • Transmission – It enters to human body through the bites of infected mosquitos to humans.
  • Transmitted by – Different types of mosquitoes,
    • Culex – Widespread across urban and semi-urban areas.
    • Anopheles – Found in rural areas.
    • Aedes – Endemic in the islands of Pacific.
  • Risk factors – It is usually acquired in childhood.
  • TreatmentIt is possible to stop the spread of the infection through preventive chemotherapy.
  • WHO recommendation – It recommended chemotherapy strategy for lymphatic filariasis elimination is Mass Drug Administration (MDA).

Mass Drug Administration (MDA) involves administering an annual dose of medicines to the entire at-risk population.

  • 5-pronged strategy to ensure that Lymphatic Filariasis (LF) is eliminated much ahead of the Sustainable Development Goal of 2030.

Mass Drug Administration (MDA)  Campaign in India

  • Goal To reduce the spread of LF by eliminating the microscopic filarial parasites present in the bloodstream of infected individuals.
  • Coverage – 111 endemic districts across 13 states,
    • Andhra Pradesh, Assam, Bihar, Chhattisgarh, Gujarat, Jharkhand, Karnataka, Kerala, Madhya Pradesh, Maharashtra, Odisha, Uttar Pradesh, and West Bengal.
  • Medication regimenDouble Drug (DA) Diethylcarbamazine Citrate (DEC) and Albendazole.
  • Triple Drug (IDA) – Ivermectin, Diethylcarbamazine Citrate (DEC), and Albendazole.

References

  1. PIB| Mass Drug Administration (MDA) Campaign for Lymphatic Filariasis (LF)
  2. WHO| Lymphatic Filariasis (LF)
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