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19/04/2019 - Science and Technology

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April 19, 2019

What is meant by Genome sequencing? How will it impact the  health care ecosystem in India? Explain with relevant illustrations(200 Words)

Refer - The Hindu

Enrich the answer from other sources, if the question demands.

4 comments
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IAS Parliament 6 years

KEY POINTS

·        Genome sequencing is figuring out the order of DNA nucleotides, or bases, in a genome—the order of As, Cs, Gs, and Ts that make up an organism's DNA.

·        Today, DNA sequencing on a large scale,the scale necessary for ambitious projects such as sequencing an entire genome is mostly done by high-tech machines.

·        A DNA sequence that has been translated from life's chemical alphabet into our alphabet of written letters.

·        In an indigenous genetic mapping effort, nearly 1,000 rural youth from the length and breadth of India will have their genomes sequenced by the Council of Scientific and Industrial Research (CSIR).

·        The project aims at educating a generation of students on the “usefulness” of genomics, educating them about genomics and putting a system in place that allows them to access information revealed by their genome.

·        It opens a fresh perspective on the link between disease and the unique genetic make-up of each individual. Diseases — including cystic fibrosis, thalassemia — are known to be the result of a single gene malfunctioning.

·        While genes may render some insensitive to certain drugs, genome sequencing has shown that cancer too can be understood from the viewpoint of genetics, rather than being seen as a disease of certain organs.

Illustrations

·        Genome sequencing helps to develop the field of pharmacology by understanding the disease structure accurately and contributes to the development of high quality drugs and medicines.

·        India has been the largest generic drug supplier to Asia and Africa.

·        Genome asia 100k initiative provides sequencing of around 50000 genome of Indians to understand the evolution of humans and associated disease.

 

Sandeep 6 years

Kindly review thanks

IAS Parliament 6 years

Good answer. Try to include genome asia 100k intiative. Keep Writing.

Vandana 6 years

Kindly review . Thanks.

aishwarya 6 years

nicely written...but you can also add how sequencing is done because examiner wants you to illustrate it

IAS Parliament 6 years

Good answer. Keep Writing.

Melvin 6 years

Kindly Review,Thank You.

IAS Parliament 6 years

Try to give some illustrations on genome sequencing like Earth biogenome project, Genome asia 100k initiative. Keep Writing.

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